MESENCHYMAL STEM CELL THERAPY

Make an appointment now to find out if Stem Cell Therapy is right for you. ( click here)

Although the science behind stem cell therapy for joint and spine pain is still young, it holds much promise.

Mesenchymal Stem Cells are isolated from the bone marrow of the iliac crest and from fat. They contain the ultimate potential of becoming the cells of the tissue they are injected in! With injection of stem cells into injured joints and their surrounding supporting ligaments and tendons, formation of new tissue and healing of injury occurs.

Multiple stem cell studies demonstrate superior efficacy for patient-reported outcomes compared with controls at final follow-up (range 24-48 months).

Superior outcomes on follow up X-ray evaluations were found favoring stem cell injections. Superior outcomes on evaluation of biopsied samples of cartilage and/or improved arthroscopically scored healing rates were also seen. We offer Mesenchymal Stem Cell treatment for arthritis and trauma related injury of all the major joints of the limbs as well as the cervical, thoracic, lumbar and sacroiliac spine.

How Are We Different?

Dr Kaplan and Dr Speciale with Fat Stem Cell concentrate
  • Our technique of Stem Cell extraction is fast and virtually painless
  • Unlike some orthopedic clinics that utilize a one-and-done intra-articular joint technique that produces limited results, our osteopathic approach incorporates treatment of all stabilizing tendons and ligaments inside and outside the injured joint for the most comprehensive healing and stabilizing results.
  • Our Stem cell injections are combined with prolotherapy dextrose injections that have been shown to activate and make stem cell concentrate more potent and effective.
  • We use high definition ultrasound for diagnosis and guidance of all injections.

What are Mesenchymal Stem Cells:

Mesenchymal Stem Cells are an abundant source of self-renewing, multipotent undifferentiated cells that  can be readily isolated from bone marrow and adipose tissue. These cells can then differentiate into bone, cartilage, fat and tendon. Their use has been steadily growing for regeneration and repair of injured joint tissues. These cells in addition to their differentiation potential, exhibit a growth promoting, anti-inflammatory and immune mediating activity shown to attenuate the mediators of joint destruction as well as promote their repair.

Stem Cells use vs PRP( platelet rich plasma).

Several studies demonstrate superior efficacy of healing when Stem cell therapy is combined with platelet rich plasma.

A recent case report featured complete healing of avascular necrosis (severe degenerative hip condition caused by lack of blood flow to the cartilage) with a combination of Stem Cell and PRP injections done over several months.

Studies are lacking in comparing PRP against Stem Cell injections alone at this time, but it stands to reason that when the stem cells are extracted directly from the bone marrow, their influence on the regeneration of injured tissue will be much stronger then the use of the platelet carried growth factors found in PRP alone.

Our injection technique: 

We use high-resolution ultrasound imaging for evaluation of the affected body areas and ultrasound guidance of the Stem Cell injections into these regions.

How do we make a decision on when to use prolotherapy, PRP and Stem Cells therapy.

Prolotherapy (linked to the prolo page) is used for mild to moderate degenerative joint and spine conditions where there is more ligament then cartilage damage and lack of joint stability is the main issue.

Platelet Rich Plasma( linked to PRP page)  injections are used for moderate to advanced degenerative joint conditions with significant wear and tear of the cartilage.

Stem Cell therapy is used in advanced degenerative conditions with severe wear of the cartilage and in cases where PRP treatment alone did not provide adequate recovery of function and reduction of pain.